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Whilst lower-rely MBL not often progresses to CLL, significant-rely MBL progresses to CLL demanding therapy at a fee of 1% to two% each year. Superior-depend MBL is distinguished from Rai 0 CLL based on whether or not the B-cell rely is over or underneath five × 109/L. While folks with the two large-depend MBL and CLL Rai stage 0 are at enhanced d